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KMID : 0043320070300060691
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Archives of Pharmacal Research
2007 Volume.30 No. 6 p.691 ~ p.694
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Norditerpenoid and Dianthramide Glucoside Alkaloids from Cultivated Aconitum Species from Korea
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Lee So-Young
Shim Sang-Hee
Kim Ju-Sun
Lee Jae-Hyun
Lee Ho-Young
Jung Da-Young
Ha Hye-Kyung
Kim Chung-Sook
Kang Sam-Sik
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Abstract
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A new norditerpene alkaloid named 8-O-methylhypaconine (1) was isolated along with twelve known alkaloids from the underground parts of an unknown species of Aconitum plant cultivated in Korea. Among the known alkaloids, two dianthramide glucosides, N-(2’-β-glucopyranosyl- 5’-hydroxysalicyl)-5-hydroxyanthranilic acid methyl ester (2) and N-(2’-β-glucopyranosyl- 5’-hydroxysalicyl)-5-hydroxy-6-methoxyanthranilic acid methyl ester (3), were isolated from Aconitum plants for the first time. The structures were established on the basis of chemical and spectroscopic methods.
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KEYWORD
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Aconitum species, Ranunculaceae, Norditerpenoid alkaloid, Dianthramide glucoside
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